When to Perform Prostate Biopsy?


  • No strict PSA cut-off is recommended
  • Different variables like Digital Rectal Examination, Total PSA level, Free/Total PSA ratio, Age, Race and Family History of Prostate Cancer are being used to decide when to perform Prostate Biopsy.
  • Prostate Cancer Risk Calculators like PCPT RC-2.0, Sunnybrook Nomogram and ERSPC Calculators are being used by some urologists to help make a joint physician- patient decision to perform biopsy.