Common Medications

Page updated Winter 2021.
DisclaimerMedicine is an ever-changing science.  We have been witnessing changes in diagnostic and therapeutic modalities and guidelines during last several years. We have used sources believe to be reliable for purpose of this website including AUA guidelines, EAU guidelines, NCCN guidelines, Campbell-Walsh-Wein Urology, UpToDate, Merck Manual, Lexi-Comp, FDA website, and other reputable resources. However, due to possibility of human error or changes in medicine, readers are required to confirm the information provided in this website with other sources. Readers are specially required to read all parts of the product information sheet included in the package of each drug they plan to administer and follow those instructions. Readers are also needed to follow instructions of FDA and other regulatory bodies and their own department in this regard. Authors can cite information provided in our textbooks or they need to cite the original resources. This website serves as a general framework. We and other users would adjust the approach per departments policies and patients situation. Forms can be used by other health care professionals.

Cystitis

Nitrofurantoin monohydrate (Macrobid)

100 mg twice daily for 5 days

Trimethoprim-sulfamethoxazole (Bactrim, Septra)

160/800 mg twice-daily for 3 days.

Pyelonephritis


Oral antimicrobial therapy in uncomplicated pyelonephritis

Ciprofloxacin (Cipro)- 500 mg bid for 7 days

Levofloxacin (Levaquin)- 750 daily for 5 days.


Parenteral antimicrobial therapy for pyelonephritis


For 10-14 days

First-line treatment

Ciprofloxacin (Cipro)

400 mg b.i.d- Not a good choice in complicated PN.

Levofloxacin (Levaquin)

 750 mg daily- Not a good choice in complicated PN.

Ceftriaxone (Rocephin)- 1-2 g daily

Second-line treatment

Cefepime (Maxipime)

1-2 g b.i.d-- In sepsis 2 g b.i.d

Piperacillin/tazobactam (Zosyn)

2.5-4.5 g t.i.d- In sepsis 4.5 g t.i.d

Third-line treatment

Meropenem (Merrem)- 1 g t.i.d

Fournier’s Gangrene

Piperacillin/tazobactam (Zosyn)- 4.5 g every 6-8 h IV  plus

Vancomycin (Vancocin)- 15 mg/kg every 12 h

or

Meropenem (Merrem) -  1 g every 8 h IV

Candiduria

Asymptomatic Candiduria- Pre-procedural 

Fluconazole: 

PO, 400 mg (6 mg/kg) daily. Several days before and after the procedure.

Symptomatic Candida Cystitis

Fluconazole

200 mg (3 mg/kg), PO, daily for 2 weeks.

Fluconazole-resistant C. glabrata

Amphotericin B deoxycholate (Conventional amphotericin B )

0.3–0.6 mg/kg IV daily for 1–7 days   or

Flucytosine (Ancobon)

PO, 25 mg/kg 4 times daily for 7–10 days 

C. krusei

Amphotericin B deoxycholate, 0.3–0.6 mg/kg daily, for 1–7 days

Symptomatic Ascending Candida  Pyelonephritis

Fluconazole

200–400 mg (3–6 mg/kg), PO daily for 2 weeks

Fluconazole-resistant C. glabrata

Amphotericin B deoxycholate, 0.3–0.6 mg/kg daily for 1–7 day

with or without oral Flucytosine

or

Flucytosine, 25 mg/kg 4 times daily for 2 weeks

C. krusei

Amphotericin B deoxycholate, 0.3–0.6 mg/kg daily, for 1–7 days 

Urinary Stone Medication

HydrochlorothiazideInitial: 25 mg once daily; titrate to usual effective dose of 50 to 100 mg/day in 1 to 2 divided doses.

Potassium citrate: 30- 60 mEq/day. 10 to 20 mEq orally with each meal

Allopurinol: 300 mg/day

Tiopronin: Initial: 800 mg/day in 3 divided doses; average dose: 1,000 mg/day. Goal of treatment: cystine level to <250 mg/L.
Pre-op Antibiotics

Antibiotics List

Cefazolin (Ancef)

<120 kg: 2 g IV

≥ 120 kg  3 g IV

Intervals: q 4 hours, if needed.

Ampicillin (Ampi)

2 g IV 

Ampicillin/sulbactam (Unasyn)

3 g IV

Intervals: q 2 hours, if needed

Cefoxitin (Mefoxin)

2 g IV

Intervals: q 2 hours, if needed

Cefotetan (Cefotan)

2 g IV

Intervals: q 6 hours, if needed

Ciprofloxacin (Cipro)

500 mg PO

400 mg IV

Intervals: N/A


Allergy to Penicillin or Cephalosporin

Combination of following Antibiotics to cover Gram+, Gram - , and Anaerobes, depending on the case. 

Clindamycin (Cleocin)

900 mg IV

Vancomycin (Vancocin)

15 mg/kg IV- Not to exceed 2 g

Infusion should be started 1-2 hours before surgery.

Gentamicin (Garamycin)

5 mg/kg IV

Ciprofloxacin (Cipro)

400 mg IV

Infusion should be started 1-2 hours before surgery.

Levofloxacin (Levaquin)

500 mg IV

Infusion should be started 1-2 hours before surgery.

Aztreonam (Azactam)

2 g IV

Metronidazole (Flagyl)

500 mg IV

Genital Herpes

First Clinical Episode

Acyclovir 400 mg orally three times a day for 7–10 days
OR

Acyclovir 200 mg orally five times a day for 7–10 days
OR

Valacyclovir 1 g orally twice a day for 7–10 days
OR

Famciclovir 250 mg orally three times a day for 7–10 days


Episodic Treatment  for Recurrent Genital Herpes

Acyclovir 400 mg orally three times a day for 5 days
OR

Acyclovir 800 mg orally twice a day for 5 days
OR

Acyclovir 800 mg orally three times a day for 2 days
OR

Valacyclovir 500 mg orally twice a day for 3 days
OR

Valacyclovir 1 g orally once a day for 5 days
OR

Famciclovir 125 mg orally twice a day for 5 days
OR

Famciclovir 1 gram orally twice daily for 1 day
OR

Famciclovir 500 mg orally once followed by 250 mg twice daily
for 2 days

Suppressive Treatment for Recurrent Genital Herpes

Acyclovir 400 mg orally twice a day
OR

Valacyclovir 500 mg orally once a day
OR

Valacyclovir 1 g orally once a day
OR

Famciclovir 250 mg orally twice a day for 7–10 days


Benign Prostatic Hyperplasia

α-Blockers

Tamsulosin (Flomax)0.4–0.8 mg qd

Silodosin (Rapaflo)8 mg qd

Alfuzosin (Uroxatral)10 mg qd

Terazosin (Hytrin)5 or 10 mg qd

Doxazosin IR (Cardura)2–8 mg qd

Doxazosin SR (Cardura XL)4 or 8 mg qd

5α-Reductase Inhibitors

Finasteride (Proscar)5 mg qd

Dutasteride (Avodart)0.5 mg qd

Antimuscarinic Drugs for LUTS

Oxybutynin IR (Ditropan IR)-  2.5-, 5-mg, 3-4/day (max 20 mg/d)

Oxybutynin ER (Ditropan XL)- 5-,10-,15-mg,daily (max 20 mg/d)

Tolterodine IR (Detrol)-  1-, 2-mg, bid

Tolterodine ER (Detrol LA) - 2-mg, 4-mg, daily

Solifenacin (Vesicare)-  5-, 10-mg, daily

Darifenacin ER (Enablex)-  7.5-, 15-mg, daily

Fesoterodine ER (Toviaz)-  4-, 8-mg, daily

Trospium IR (Sanctura)- 20-mg, bid

Trospium ER (Sanctura XR)- 60-mg, daily

Overactive Bladder- Other Meds

β3-adrenoceptor Agonists

Mirabegron (Myrbetriq):  25 mg PO daily

Erectile Dysfunction

Oral Meds

Sildenafil (Viagra)-  25, 50, 100 mg

Tadalafil (Cialis)-  5, 10, 20 mg

Vardenafil (Levitra)-  5, 10, 20 mg

Avanafil (Stendra)-  50, 100, 200 mg

Intracavernosal Injections

Alprostadil (Caverject)-  5–40 μg/mL

Alprostadil + phentolamine (Bimix)20 μg/mL + 0.5 mg/mL

Alprostadil + papaverine + phentolamine (Trimix)- 10 μg/mL + 30 mg/mL + 1.0 mg/mL

  1. Testosterone Deficiency
  2. Aromatase inhibitors
  3. Anastrozole (Arimidex): 1 mg PO, 3/week (M/W/F)
SERMs

Clomiphene (Clomid): Start with 25 mg  PO, 3 times per week (M/W/F) and slowly titrate up to 50 mg once a day as needed. 

Human chorionic gonadotropin (hCG)

1,500-5,000 IU administered IM or SC twice weekly

Intramuscular Testosterone Injections

Short acting:

Testosterone cypionate (Depo-Testosterone) 

IM- 50- 200mg every 7 -14 days. Initial dose: 100 mg

Testosterone enanthate (Delatestryl): Same as above agent.

Long acting:

Testosterone undecanoate (Aveed)

750mg injection at weeks 0, 4, and every 10 weeks thereafter.

Transdermal Testosterone Gel

1% topical testosterone gel (Androgel, Testim, Vogelxo)

50 to 100 mg daily to shoulders, and upper arms

1.62% topical testosterone gel (Androgel): 20.25 to 81 mg daily

Premature Ejaculation

Topical Therapies

Lidocaine 2.5%/prilocaine 2.5% (EMLA Cream)20 to 30 minutes pre-intercourse

Selective Serotonin Reuptake Inhibitor

  1. FluoxetineProzac20-40 mg/day
    ParoxetinePaxil10, 20, 40 mg/day or 20 mg 3 -4 h before sex 
    SertralineZoloft50 to 200 mg/day or 50 mg 4 to 8 h before sex 
    Second Line Treatment
  2. Tramadol: On demand: 20-100 mg